Expression and clinical relevance of paired box protein 7 and sex determining region Y-box 2 in canine corticotroph pituitary adenomas. Issue 3 (June 2015)

• Record Type: Journal Article
• Authors: van Rijn, Sarah J.; Pouwer, Marianne G.; Tryfonidou, Marianna A.; Grinwis, Guy C.M.; van der Bend, Joanne E.E.; Beukers, Pauline E.P.F.; Vastenhout, Nadie; Drouin, Jacques; Penning, Louis C.; Meij, Björn P.
• Is Part Of: Veterinary journal. Volume 204:Issue 3(2015)
• Page Start: 315
• Page End: 321
• Publication Date: 2015-06
• Subjects: Veterinary medicine -- Periodicals; 636
• DOI: 10.1016/j.tvjl.2015.04.014
• Languages: English
• ISSNs: 1090-0233

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">The expression of Pax7 and Sox2 was studied in canine pituitary adenomas.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Pax7 expression was higher in enlarged pituitaries than in non-enlarged pituitaries.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">Downstream targets of Pax7 were significantly down regulated in adenoma samples.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">Pax7 and Sox2 are unsuitable as clinical prognosticators in canine Cushing's disease.</p> </list-item> </list> </p> </sec> </abstract>