Prevalence and Risk Factors of Cognitive Impairment in Parkinson Disease. Issue 17 (May 2015)

• Record Type: Journal Article
• Authors: Huang, Yu-Ching; Wu, Shwu-Tzy; Lin, Juei-Jueng; Lin, Che-Chen; Kao, Chia-Hung; Yong., Li
• Is Part Of: Medicine. Volume 94:Issue 17(2015)
• Publication Date: 2015-05
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000000782
• Languages: English
• ISSNs: 0025-7974

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Abstract</title> <p>The aim of this study was to evaluate the Parkinson disease (PD) prevalence of cognitive impairment in Taiwan.</p> <p>The case–control study consisted of 6177 cognitive impairment patients and 24, 708 noncognitive impairment as controls for the period of 2006 to 2010 and both of the groups aged ≥50 years. The multivariable logistic regression analyses were used to estimate the odds ratio (OR) for cognitive impairment, and the 95% confidence intervals (CIs) among patients with PD were compared with those of non-PD patients.</p> <p>PD (adjusted odds ratio [aOR] is 3.07, 95% CI 2.76–3.41) is the one of the most contributed risk factors for cognitive impairment. Besides, we found a remarkable result of the diagnosed cognitive impairment of PD that was found highest in the first 6 months (aOR 11.98, 95% CI 8.51–16.86) and then decrease the incident year by year. The PD prevalence in a patient with cognitive impairment in our data present is 12.1% lower than those with truly dementia published previously and documented by western studies.</p> <p>We found a remarkable result of the diagnosed cognitive impairment of PD that was found highest in the first 6 months and then decrease the incident year by year.</p> </sec> </abstract>