Differential proteome–metabolome profiling of YCA1-knock-out and wild type cells reveals novel metabolic pathways and cellular processes dependent on the yeast metacaspase1. Issue 6 (19th June 2015)

• Record Type: Journal Article
• Authors: Ždralević, Maša; Longo, Valentina; Guaragnella, Nicoletta; Giannattasio, Sergio; Timperio, Anna Maria; Zolla, Lello
• Is Part Of: Molecular bioSystems. Volume 11:Issue 6(2015:Jun.)
• Page Start: 1573
• Page End: 1583
• Publication Date: 2015-06-19
• Subjects: Molecular biology -- Periodicals; Biochemistry -- Periodicals; 571.7405
• DOI: 10.1039/c4mb00660g
• Languages: English
• ISSNs: 1742-206X

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjp0c4p74" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A combined proteomic and metabolomic approach revealed new non-apoptotic roles of the metacaspase <italic>YCA1</italic> gene in <italic>Saccharomyces cerevisiae</italic>, highlighting its involvement in the cell metabolism and stress response.</p> </abstract>