Catalytic CH Bond Addition of Pyridines to Allenes by a Rare‐Earth Catalyst. Issue 23 (21st April 2015)

• Record Type: Journal Article
• Authors: Song, Guoyong; Wang, Baoli; Nishiura, Masayoshi; Hou, Zhaomin
• Is Part Of: Chemistry. Volume 21:Issue 23(2015)
• Page Start: 8394
• Page End: 8398
• Publication Date: 2015-04-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201501121
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The catalytic CH addition of pyridines to allenes has been achieved for the first time by using a half‐sandwich scandium catalyst, thus constituting a straightforward and atom‐economical route for the synthesis of alkenylated pyridine derivatives. The reaction proceeded regio‐ and stereoselectively, affording a new family of alkenylated pyridine compounds which are otherwise difficult to synthesize. A cationic Sc‐η²‐pyridyl species was isolated and confirmed to be a key catalyst species in this transformation.</p> </abstract>