Granulomatous reactions after injections of multiple aesthetic micro‐implants in temporal combinations: a complication of filler addiction. (28th October 2014)

• Record Type: Journal Article
• Authors: Rongioletti, F.; Atzori, L.; Ferreli, C.; Pau, M.; Pinna, A. L.; Mercuri, S. R.; Aste, N.; Fraitag, S.
• Is Part Of: Journal of the European Academy of Dermatology and Venereology. Volume 29:Number 6(2015:Jun.)
• Page Start: 1188
• Page End: 1192
• Publication Date: 2014-10-28
• Subjects: Dermatology -- Periodicals; Sexually transmitted diseases -- Periodicals; 616.5
• DOI: 10.1111/jdv.12788
• Languages: English
• ISSNs: 0926-9959

Abstract

<abstract abstract-type="main" id="jdv12788-abs-0001"> <title>Abstract</title> <sec id="jdv12788-sec-0001" sec-type="section"> <title>Background</title> <p>Granulomatous reaction is a well‐known complication following soft filler procedures. However, the diagnosis of filler‐induced granulomas may be challenging because of the occasional reluctance of patients to report the previously performed aesthetic procedure.</p> </sec> <sec id="jdv12788-sec-0002" sec-type="section"> <title>Objective</title> <p>To describe a new clinical situation in which some patients, in the quest for physical perfection, become addicted to multiple sequential cosmetic injections, increasing the risk of adverse reactions.</p> </sec> <sec id="jdv12788-sec-0003" sec-type="section"> <title>Methods</title> <p>We describe three women who developed diffuse facial nodular tumefaction after multiple procedures of filler injections into their face that occurred at different times in the previous years.</p> </sec> <sec id="jdv12788-sec-0004" sec-type="section"> <title>Results</title> <p>Histopathology showed a granulomatous reaction including different combined substances that were identified with different types of micro‐implants in the same biopsy.</p> </sec> <sec id="jdv12788-sec-0005" sec-type="section"> <title>Conclusions</title> <p>Excessive demand of multiple cosmetic injections may increase the frequency of skin granulomatous reactions and can be included in the spectrum of similar addictive dysmorphophobic behaviours. Histopathology is the best mean to achieve the diagnosis.</p> </sec> </abstract>