Epilepsy Treatment: Controlling Epileptiform Activity with Organic Electronic Ion Pumps (Adv. Mater. 20/2015). (May 2015)

• Record Type: Journal Article
• Authors: Williamson, Adam; Rivnay, Jonathan; Kergoat, Loïg; Jonsson, Amanda; Inal, Sahika; Uguz, Ilke; Ferro, Marc; Ivanov, Anton; Sjöström, Theresia Arbring; Simon, Daniel T.; Berggren, Magnus; Malliaras, George G.; Bernard, Christophe
• Is Part Of: Advanced materials. Volume 27:Number 20(2015)
• Page Start: 3097
• Page End: 3097
• Publication Date: 2015-05
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201570133
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adma201570133-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Organic electronic ion pumps (OEIPs) convert electrical current into ionic current. When in contact with neural tissue, this ionic current can be used to control the activity of neural networks. G. G. Malliaras, C. Bernard, and co‐workers develop an OEIP capable of delivering the inhibitory neurotransmitter gamma‐aminobutyric acid (GABA), as described on page 3138. The ability of the OEIP to locally suppress epileptiform activity in the mouse hippocampus is demonstrated. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgjnfxc425" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>