Mitochondrial replacement therapy: Cautiously replace the master manipulator. (27th February 2015)

• Record Type: Journal Article
• Authors: Gemmell, Neil; Wolff, Jonci N.
• Is Part Of: BioEssays. Volume 37:Number 6(2015:Jun.)
• Page Start: 584
• Page End: 585
• Publication Date: 2015-02-27
• Subjects: Molecular biology -- Periodicals; Cytology -- Periodicals; Developmental biology -- Periodicals; 572.8
• DOI: 10.1002/bies.201500008
• Languages: English
• ISSNs: 0265-9247

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Mitochondria, the powerhouses of our cells, are essential to life. Normal mitochondrial function is achieved through the cooperative interaction of the nuclear and mitochondrial genomes. New IVF approaches intended to circumvent devastating mitochondrial disease look set to change the ancient pattern of mtDNA inheritance and interaction with unknown consequences. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgjnfw7nq1" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>