Acylsulfonamide‐Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH1. Issue 22 (14th April 2015)
- Record Type:
- Journal Article
- Title:
- Acylsulfonamide‐Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH1. Issue 22 (14th April 2015)
- Main Title:
- Acylsulfonamide‐Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH1
- Authors:
- Mizuhara, Tsukasa
Saha, Krishnendu
Moyano, Daniel F.
Kim, Chang Soo
Yan, Bo
Kim, Young‐Kwan
Rotello, Vincent M. - Abstract:
- <abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A nanoparticle design featuring pH‐responsive alkoxyphenyl acylsulfonamide ligands is reported herein. As a result of ligand structure, this nanoparticle is neutral at pH 7.4, becoming positively charged at tumor pH (<6.5). The particle uptake and cytotoxicity increase over this pH range. This pH‐controlled uptake and toxicity makes this particle a promising tool for tumor selective therapy.</p> </abstract>
- Is Part Of:
- Angewandte Chemie international edition. Volume 54:Issue 22(2015)
- Journal:
- Angewandte Chemie international edition
- Issue:
- Volume 54:Issue 22(2015)
- Issue Display:
- Volume 54, Issue 22 (2015)
- Year:
- 2015
- Volume:
- 54
- Issue:
- 22
- Issue Sort Value:
- 2015-0054-0022-0000
- Page Start:
- 6567
- Page End:
- 6570
- Publication Date:
- 2015-04-14
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3773 ↗
http://www.interscience.wiley.com/jpages/1433-7851 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/anie.201411615 ↗
- Languages:
- English
- ISSNs:
- 1433-7851
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 3992.xml