Diffusion Weighted Imaging and Apparent Diffusion Coefficient in 3 Tesla Magnetic Resonance Imaging of Breast Lesions. (28th May 2015)

• Record Type: Journal Article
• Authors: Caivano, Rocchina; Villonio, Antonio; D' Antuono, Felice; Gioioso, Matilde; Rabasco, Paola; Iannelli, Giancarlo; Zandolino, Alexis; Lotumolo, Antonella; Dinardo, Giuseppina; Macarini, Luca; Guglielmi, Giuseppe; Cammarota, Aldo
• Is Part Of: Cancer investigation. Volume 33:Number 5(2015)
• Page Start: 159
• Page End: 164
• Publication Date: 2015-05-28
• Subjects: Cancer -- Periodicals; Oncology -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- Periodicals; 616.994
• DOI: 10.3109/07357907.2015.1019674
• Languages: English
• ISSNs: 0735-7907

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p> <italic>Objective</italic>: To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions. <italic>Methods:</italic> 110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results. <italic>Results</italic>: MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm²/s, respectively (<italic>p</italic> &lt; .05). <italic>Conclusions</italic>: DWI and ADC-values could help distinguishing malignant and benign breast masses.</p> </abstract>