Mode of delivery changes oxidative and antioxidative properties of human milk: a prospective controlled clinical investigation. (April 2015)

• Record Type: Journal Article
• Authors: Şimşek, Yavuz; Karabiyik, Pinar; Polat, Kubra; Duran, Zeynep; Polat, Alaaddin
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 28:Number 6(2015)
• Page Start: 734
• Page End: 738
• Publication Date: 2015-04
• Subjects: Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.3109/14767058.2014.932345
• Languages: English
• ISSNs: 1476-7058

Abstract

<abstract> <title>Abstract</title> <p> <italic>Objective</italic>: To evaluate the influence of delivery mode on oxidative stress in human breast milk.</p> <p> <italic>Methods</italic>: Thirty-three women who delivered by vaginal birth and 55 women who underwent cesarean section (CS) were included in this study. Colostral samples were collected on the second day after delivery. Total antioxidative status (TAS), total oxidative status (TOS), oxidative stress index (OSI), malonyldialdehyde (MDA), and glutathione peroxidase (GSH-Px) levels were determined and compared.</p> <p> <italic>Results</italic>: Colostrum TAS was significantly higher in women of vaginal birth, than in women with CS (<italic>p</italic> &lt; 0.001). Milk TOS and OSI were found to be significantly increased in women with CS under general anesthesia. A marked increase in colostral GSH-Px levels after vaginal delivery was also noticed (<italic>p</italic> &lt; 0.001).</p> <p> <italic>Conclusion</italic>: This study revealed that vaginal birth is associated with decreased oxidative stress in colostrum than CS, which suggest that mode of delivery plays an important role in the antioxidative production of breast milk.</p> </abstract>