Thermo/redox/pH-triple sensitive poly(N-isopropylacrylamide-co-acrylic acid) nanogels for anticancer drug delivery. Issue 20 (28th May 2015)

• Record Type: Journal Article
• Authors: Zhan, Yuan; Gonçalves, Mara; Yi, Panpan; Capelo, Débora; Zhang, Yuhong; Rodrigues, João; Liu, Changsheng; Tomás, Helena; Li, Yulin; He, Peixin
• Is Part Of: Journal of materials chemistry. Volume 3:Issue 20(2015)
• Page Start: 4221
• Page End: 4230
• Publication Date: 2015-05-28
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c5tb00468c
• Languages: English
• ISSNs: 2050-750X

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn2zhwnm" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Doxorubicin is effectively loaded into disulfide-crosslinked poly(<italic>N</italic>-isopropylacrylamide-<italic>co</italic>-acrylic acid) nanogels, which can be triggerably released in a heating or reducing acidic tumor microenvironment.</p> </abstract>