Self-assembled targeted folate-conjugated eight-arm-polyethylene glycol–betulinic acid nanoparticles for co-delivery of anticancer drugs. Issue 18 (14th May 2015)

• Record Type: Journal Article
• Authors: Dai, Lin; Cao, Xin; Liu, Ke-Feng; Li, Chun-Xiao; Zhang, Gui-Feng; Deng, Li-Hong; Si, Chuan-Ling; He, Jing; Lei, Jian-Du
• Is Part Of: Journal of materials chemistry. Volume 3:Issue 18(2015)
• Page Start: 3754
• Page End: 3766
• Publication Date: 2015-05-14
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c5tb00042d
• Languages: English
• ISSNs: 2050-750X

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn2zhkrt" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Folate-8arm-PEG–betulinic acid nanoparticles prepared <italic>via</italic> a self-assembly process are stable in circulation, resulting in the EPR effect of solid tumors, and are efficiently internalized by cancer cells.</p> </abstract>