QSAR-guided semi-synthesis and in vitro validation of antiplasmodial activity in ursolic acid derivatives1. Issue 41 (7th May 2015)

• Record Type: Journal Article
• Authors: Kalani, Komal; Cheema, Harveer Singh; Tripathi, Himanshu; Khan, Feroz; Daroker, M. P.; Srivastava, Santosh Kumar
• Is Part Of: RSC advances. Volume 5:Issue 41(2015)
• Page Start: 32133
• Page End: 32143
• Publication Date: 2015-05-07
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c4ra13709d
• Languages: English
• ISSNs: 2046-2069

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn2nxwvc" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />As a part of antimalarial drug discovery programme, a QSAR model was developed for the prediction of antiplasmodial activity in ursolic acid derivatives, followed by semi-synthesis of virtually active derivatives and their biological evaluation.</p> </abstract>