Pd-catalyzed enantioselective intramolecular α-arylation of α-substituted cyclic ketones: facile synthesis of functionalized chiral spirobicycles1. Issue 17 (7th May 2015)

• Record Type: Journal Article
• Authors: Fan, Lulu; Takizawa, Shinobu; Takeuchi, Yoshiki; Takenaka, Kazuhiro; Sasai, Hiroaki
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 17(2015)
• Page Start: 4837
• Page End: 4840
• Publication Date: 2015-05-07
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00382b
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn2npv2v" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Synthesis of chiral spirocyclic ketones was accomplished <italic>via</italic> the Pd-catalyzed intramolecular α-arylation of α-substituted cyclic ketones. The obtained spirocyclic ketone could be converted into an acid–base organocatalyst.</p> </abstract>