An artificial heme-enzyme with enhanced catalytic activity: evolution, functional screening and structural characterization1. Issue 17 (7th May 2015)

• Record Type: Journal Article
• Authors: Vitale, Rosa; Lista, Liliana; Cerrone, Corinne; Caserta, Giorgio; Chino, Marco; Maglio, Ornella; Nastri, Flavia; Pavone, Vincenzo; Lombardi, Angela
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 17(2015)
• Page Start: 4859
• Page End: 4868
• Publication Date: 2015-05-07
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00257e
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn2npk62" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The rational refinement of function into the heme-protein model Mimochrome VI (MC6) resulted in a new analogue, Fe^III-E²L(TD)-MC6, with an improved peroxidase activity.</p> </abstract>