Azasugar inhibitors as pharmacological chaperones for Krabbe disease12. Issue 5 (20th May 2015)

• Record Type: Journal Article
• Authors: Hill, Chris H.; Viuff, Agnete H.; Spratley, Samantha J.; Salamone, Stéphane; Christensen, Stig H.; Read, Randy J.; Moriarty, Nigel W.; Jensen, Henrik H.; Deane, Janet E.
• Is Part Of: Chemical science. Volume 6:Issue 5(2015:May)
• Page Start: 3075
• Page End: 3086
• Publication Date: 2015-05-20
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5sc00754b
• Languages: English
• ISSNs: 2041-6520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn2njgm1" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Modified azasugar molecules have been synthesized and characterized as excellent pharmacological chaperone candidates to treat the neurodegenerative disorder Krabbe disease.</p> </abstract>