Evaluation of the anti-inflammatory/chondroprotective activity of aldose reductase inhibitors in human chondrocyte cultures. Issue 5 (13th May 2015)

• Record Type: Journal Article
• Authors: Panico, Annamaria; Maccari, Rosanna; Cardile, Venera; Avondo, Sergio; Crascì, Lucia; Ottanà, Rosaria
• Is Part Of: MedChemComm. Volume 6:Issue 5(2015:May)
• Page Start: 823
• Page End: 830
• Publication Date: 2015-05-13
• Subjects: Pharmaceutical chemistry -- Periodicals; 615.19
• DOI: 10.1039/c4md00556b
• Languages: English
• ISSNs: 2040-2503

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn2n2f83" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />2-Thioxo-4-thiazolidinone derivatives active as aldose reductase inhibitors were able to control key inflammatory/degenerative events induced by IL-1β in human chondrocytes, appearing to be promising candidates in the search for novel anti-inflammatory agents.</p> </abstract>