A highly-efficient palladium-catalyzed aminocarbonylation/SNAr approach to dibenzoxazepinones1. Issue 5 (12th May 2015)

• Record Type: Journal Article
• Authors: Shen, Chaoren; Neumann, Helfried; Wu, Xiao-Feng
• Is Part Of: Green chemistry. Volume 17:Issue 5(2015)
• Page Start: 2994
• Page End: 2999
• Publication Date: 2015-05-12
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c5gc00427f
• Languages: English
• ISSNs: 1463-9262

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn298sc1" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A practical protocol for the synthesis of dibenzo[<italic>b</italic>, <italic>e</italic>][1, 4]oxazepin-11(5<italic>H</italic>)-ones has been developed. By virtue of Pd-catalyzed aminocarbonylation and aromatic nucleophilic substitution, 61 examples of the desired dibenzoxazepinones were obtained in moderate to excellent isolated yields (54–92%).</p> </abstract>