"Anion clamp" allows flexible protein to impose coordination geometry on metal ions12. Issue 37 (7th May 2015)

• Record Type: Journal Article
• Authors: Wang, Minji; Lai, Tsz Pui; Wang, Li; Zhang, Hongmin; Yang, Nan; Sadler, Peter J.; Sun, Hongzhe
• Is Part Of: Chemical communications. Volume 51:Issue 37(2015)
• Page Start: 7867
• Page End: 7870
• Publication Date: 2015-05-07
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc09642h
• Languages: English
• ISSNs: 1359-7345

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjn27qr6z" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />X-ray crystal structures of human serum transferrin (77 kDa) with Yb^III or Fe^III bound to the C-lobe and malonate as the synergistic anion show that the large Yb^III ion causes the expansion of the metal binding pocket while octahedral metal coordination geometry is preserved, an unusual geometry for a lanthanide ion.</p> </abstract>