Novel highly sensitive Cu‐based SERS platforms for biosensing applications. (8th March 2015)

• Record Type: Journal Article
• Authors: Kowalska, Aneta Aniela; Kaminska, Agnieszka; Adamkiewicz, Witold; Witkowska, Evelin; Tkacz, Marek
• Is Part Of: Journal of Raman spectroscopy. Volume 46:Number 5(2015:May)
• Page Start: 428
• Page End: 433
• Publication Date: 2015-03-08
• Subjects: Raman spectroscopy -- Periodicals; 535.846
• DOI: 10.1002/jrs.4674
• Languages: English
• ISSNs: 0377-0486

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Novel surface enhanced Raman spectroscopy (SERS) platforms have been prepared and used for the bacteria detection. Unlike typical, expensive SERS platforms prepared from gold or silver, the presented platforms are prepared using copper. A new, simple, cost‐efficient and fast high pressure method is used for platform fabrication, through the decomposition of copper hydride. The platform enhancement factors are verified using the malachite green isothiocyanate as a standard. The platforms exhibit extremely high SERS enhancement factors depending on pressure used for their preparation. The calculated enhancement factors have been found in the range between 1.5 × 10⁶ and 4.6 × 10⁷. The SERS spectra reproducibility is established both across a single platform and among different platforms. The average spectral correlation coefficient (Γ) has been calculated to be 0.82. Fully characterized SERS platforms have then been used for detecting <italic>Staphylococcus aureus</italic> bacteria. These novel platforms have great potential to become excellent tools for biological or medical diagnostics as an alternative to more common silver or gold SERS platforms. Copyright © 2015 John Wiley &amp; Sons, Ltd.</p> </abstract>