Long‐term outcome of parapneumonic effusions in children: Lung function and exercise tolerance. Issue 6 (29th April 2014)

• Record Type: Journal Article
• Authors: Kontouli, Kalliopi; Hatziagorou, Elpis; Kyrvasilis, Fotis; Roilides, Emmanuel; Emporiadou, Maria; Tsanakas, John
• Is Part Of: Pediatric pulmonology. Volume 50:Issue 6(2015:Jun.)
• Page Start: 615
• Page End: 620
• Publication Date: 2014-04-29
• Subjects: Pediatric respiratory diseases -- Periodicals; Pediatrics -- Periodicals; 618.922
• DOI: 10.1002/ppul.23054
• Languages: English
• ISSNs: 8755-6863

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Summary</title> <sec id="ppul23054-sec-0001" sec-type="section"> <title>Objectives</title> <p>a: To evaluate the long‐term outcome of parapneumonic effusions (PPE) in children regarding lung function and exercise tolerance, (b) to investigate the role of bronchial asthma in the outcome of PPE.</p> </sec> <sec id="ppul23054-sec-0002" sec-type="section"> <title>Methods</title> <p>The design of the study included 51 children with PPE, at least 2 years after the initial infection. They were divided in two groups. Group A (38 children) consisted of children with PPE but without asthma prior initial infection. Group B (13 children) included children with PPE and asthma prior infection. Thirty‐six children were taken as healthy controls (group C). All children performed spirometry and a maximal incremental cardiopulmonary exercise test on cycle ergometer.</p> </sec> <sec id="ppul23054-sec-0003" sec-type="section"> <title>Results</title> <p>Children of both groups (A and B) showed statistically significant lower values in FVC%, FEV<sub>1</sub>%, and FEV<sub>1</sub>/FVC compared to controls (group C). Children of group B had also significant lower FEF<sub>25–75%</sub> values compared to controls. Children of group B had significant lower FEV<sub>1</sub>/FVC values compared to group A. All children of the three groups showed no differences in maximal exercise capacity (VO<sub>2</sub>max). Children of group A had higher respiratory equivalent to oxygen (VE/VO<sub>2</sub>) during exercise compared to healthy subjects.</p> </sec> <sec id="ppul23054-sec-0004" sec-type="section"> <title>Conclusions</title> <p>There are small effects on lung function and exercise capacity in the long‐term, among children with PPE, but of no clinical importance. Pre‐existing bronchial asthma doesn't influence the outcome significantly. <bold>Pediatr Pulmonol. 2015; 50:615–620.</bold> © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>