Copper(II)‐Triflate‐Catalyzed Oxidative Amidation of Terminal Alkynes: A General Approach to α‐Ketoamides. Issue 5 (13th March 2015)

• Record Type: Journal Article
• Authors: Kumar, Manjeet; Devari, Shekaraiah; Kumar, Arvind; Sultan, Shaista; Ahmed, Qazi Naveed; Rizvi, Masood; Shah, Bhahwal Ali
• Is Part Of: Asian journal of organic chemistry. Volume 4:Issue 5(2015:May)
• Page Start: 438
• Page End: 441
• Publication Date: 2015-03-13
• Subjects: Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201500022
• Languages: English
• ISSNs: 2193-5807

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A simple and practical method for synthesizing α‐ketoamides has been developed involving Cu(OTf)₂‐promoted oxidative amidation‐diketonization of terminal alkynes with primary/secondary amines. This method has a wide substrate scope, and atmospheric oxygen acts as the oxidant.</p> </abstract>