Safety, immunogenicity, and lot-to-lot consistency of a quadrivalent inactivated influenza vaccine in children, adolescents, and adults: A randomized, controlled, phase III trial. Issue 21 (15th May 2015)

• Record Type: Journal Article
• Authors: Cadorna-Carlos, Josefina B.; Nolan, Terry; Borja-Tabora, Charissa Fay; Santos, Jaime; Montalban, M. Cecilia; de Looze, Ferdinandus J.; Eizenberg, Peter; Hall, Stephen; Dupuy, Martin; Hutagalung, Yanee; Pépin, Stéphanie; Saville, Melanie
• Is Part Of: Vaccine. Volume 33:Issue 21(2015)
• Page Start: 2485
• Page End: 2492
• Publication Date: 2015-05-15
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.03.065
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Safety profiles in adults and children/adolescents were similar for IIV4 and IIV3.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Antibody responses to IIV4 and IIV3 were similar for corresponding strains.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">IIV4 produced comparable antibody responses in children/adolescents and adults.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">The immunogenicity of IIV4 in adults complied with EMA criteria.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Three lots of IIV4 had equivalent safety and immunogenicity profiles.</p> </list-item> </list> </p> </sec> </abstract>