Effectiveness of an oral cholera vaccine campaign to prevent clinically-significant cholera in Odisha State, India. Issue 21 (15th May 2015)

• Record Type: Journal Article
• Authors: Wierzba, Thomas F.; Kar, Shantanu K.; Mogasale, Vijayalaxmi V.; Kerketta, Anna S.; You, Young Ae; Baral, Prameela; Khuntia, Hemant K.; Ali, Mohammad; Kim, Yang Hee; Rath, Shyam Bandhu; Bhattachan, Anuj; Sah, Binod
• Is Part Of: Vaccine. Volume 33:Issue 21(2015)
• Page Start: 2463
• Page End: 2469
• Publication Date: 2015-05-15
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.03.073
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">A phase III, clinical trial conducted in Kolkata showed that Shanchol, an oral cholera vaccine, provides 65% protection against cholera over five years.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">To test the usefulness of this vaccine when deployed by public health department personnel using local resources, we conducted a mass vaccination campaign in a rural cholera-endemic area of India.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">At the end of two years, the vaccine was found to reduce cholera cases by 69%.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">This study supports widespread use of Shanchol by local health departments in cholera-affected areas of India and other nations.</p> </list-item> </list> </p> </sec> </abstract>