Susceptibility vessel sign on T2* magnetic resonance imaging and recanalization results of mechanical thrombectomy with stent retrievers: a multicentre cohort study. (19th March 2015)

• Record Type: Journal Article
• Authors: Soize, S.; Batista, A. L.; Rodriguez Regent, C.; Trystram, D.; Tisserand, M.; Turc, G.; Serre, I.; Ben Hassen, W.; Zuber, M.; Calvet, D.; Mas, J.‐L.; Meder, J.‐F.; Raymond, J.; Pierot, L.; Oppenheim, C.; Naggara, O.
• Is Part Of: European journal of neurology. Volume 22:Number 6(2015:Jun.)
• Page Start: 967
• Page End: 972
• Publication Date: 2015-03-19
• Subjects: Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; 616.8
• DOI: 10.1111/ene.12693
• Languages: English
• ISSNs: 1351-5101

Abstract

<abstract abstract-type="main" id="ene12693-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ene12693-sec-0001" sec-type="section"> <title>Background and purpose</title> <p>The susceptibility vessel sign (SVS) on T2*‐weighted magnetic resonance imaging has been reported in several studies as a negative predictor of early recanalization after intravenous thrombolysis. The meaning of SVS regarding the results of mechanical thrombectomy with stent retrievers was investigated.</p> </sec> <sec id="ene12693-sec-0002" sec-type="section"> <title>Methods</title> <p>Susceptibility vessel sign presence and length were studied in 153 acute ischaemic stroke patients (82 men; mean ± SD age 59 ± 17 years, baseline National Institutes of Health Stroke Scale score 17.2 ± 6.5) from three stroke centres, treated with either mechanical thrombectomy alone (<italic>n</italic> = 84) or bridging therapy (<italic>n</italic> = 69). Variables were compared between recanalizers, defined as thrombolysis in cerebral infarction (TICI) scores ≥2b, and non‐recanalizers (TICI<2b).</p> </sec> <sec id="ene12693-sec-0003" sec-type="section"> <title>Results</title> <p>The SVS was present in 113 (73.8%) patients. There was no association between the presence of SVS and recanalization, obtained in 86 (56.2%) patients, in the whole population [odds ratio (OR) 1.24, 95% confidence interval (CI) 0.53–2.92, <italic>P </italic>=<italic> </italic>0.84) and in treatment subgroups (bridging: OR = 0.91, 95% CI 0.29–2.87, <italic>P </italic>=<italic> </italic>1.0; thrombectomy alone: OR = 1.85, 95% CI 0.48–7.16, <italic>P </italic>=<italic> </italic>0.54). However, in SVS+ patients, recanalization decreased with SVS length (OR 0.94 for each additional mm, 95% CI 0.89–0.99; <italic>P </italic>=<italic> </italic>0.02).</p> </sec> <sec id="ene12693-sec-0004" sec-type="section"> <title>Conclusions</title> <p>The success of recanalization in acute stroke patients treated with stent retrievers was related to thrombus length but not to the presence of SVS.</p> </sec> </abstract>