Epidermal aquaporin-3 is increased in the cutaneous burn wound. Issue 4 (June 2015)

• Record Type: Journal Article
• Authors: Sebastian, R.; Chau, E.; Fillmore, P.; Matthews, J.; Price, L.A.; Sidhaye, V.; Milner, S.M.
• Is Part Of: Burns. Volume 41:Issue 4(2015)
• Page Start: 843
• Page End: 847
• Publication Date: 2015-06
• Subjects: Burns and scalds -- Periodicals; 617.11
• DOI: 10.1016/j.burns.2014.10.033
• Languages: English
• ISSNs: 0305-4179

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">In the skin, AQPs permit rapid, regulated, and selective water permeability and have been demonstrated to play a role in skin hydration, cell proliferation, migration, immunity, and wound healing.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The burn wound edge demonstrates a partial loss of the epidermal architecture representing a partial thickness burn.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">In the burn wound center there is a complete loss of the epidermis and dermis representing a full thickness burn.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Aquaporin-3 expression is absent in the burn wound center.</p> </list-item> <list-item id="lsti0030"> <label></label> <p id="par0030">There is a significant increase in the quantity of aquaporin-3 expression along the burn wound edge compared to the burn wound center.</p> </list-item> </list> </p> </sec> </abstract>