Serum IL-6, IL-10, and TNFα levels in pediatric sickle cell disease patients during vasoocclusive crisis and steady state condition. Issue 1 (March 2015)

• Record Type: Journal Article
• Authors: Sarray, Sameh; Saleh, Layal R.; Lisa Saldanha, F.; Al-Habboubi, Hebah H.; Mahdi, Najat; Almawi, Wassim Y.
• Is Part Of: Cytokine. Volume 72:Issue 1(2015)
• Page Start: 43
• Page End: 47
• Publication Date: 2015-03
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2014.11.030
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st060">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0080">We tested the association of reduced IL-10 levels with SCD vaso-occlusive crisis.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0085">IL-10 levels were significantly reduced in <italic>VOC</italic> than <italic>Steady-state</italic> SCD patients.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0090">Reduced IL-10 levels correlated with frequency, type, severity, and VOC duration.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0095">We support strong link of reduced IL-10 levels with VOC and its related parameters.</p> </list-item> </list> </p> </sec> </abstract>