Association Between Saccular Function and Gait Speed. Issue 2 (February 2015)
- Record Type:
- Journal Article
- Title:
- Association Between Saccular Function and Gait Speed. Issue 2 (February 2015)
- Main Title:
- Association Between Saccular Function and Gait Speed
- Authors:
- Layman, Andrew J.
Li, Carol
Simonsick, Eleanor
Ferrucci, Luigi
Carey, John P.
Agrawal, Yuri - Abstract:
- <abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objective</title> <p>To investigate whether otolith function (saccular and utricular) is associated with walking performance.</p> </sec> <sec> <title>Study Design</title> <p>Cross-sectional analysis of observational data collected in the Baltimore Longitudinal Study of Aging.</p> </sec> <sec> <title>Setting</title> <p>National Institute on Aging Intramural Research Program Clinical Research Unit at Harbor Hospital, Baltimore, Maryland.</p> </sec> <sec> <title>Patients</title> <p>Community-dwelling participants.</p> </sec> <sec> <title>Intervention(s)</title> <p>Cervical and ocular vestibular evoked myogenic potentials (VEMPs) were used to assess saccular and utricular function, respectively.</p> </sec> <sec> <title>Main outcome measure(s)</title> <p>Cervical and ocular VEMP latency and amplitude responses and usual, rapid, and narrow (20 cm) gait speed assessed over a 6-m course.</p> </sec> <sec> <title>Results</title> <p>In 314 participants (mean age, 73.1 yr; range, 26–96 yr), cervical VEMP amplitude mediated the association between age and gait speed—particularly narrow walk speed—in both men and women. Cervical VEMP latency had an independent association with gait speed in age-, height-, and weight-adjusted analyses, although the direction of the association differed by sex. Greater cervical VEMP latency was associated with slower usual, rapid, and narrow gait speed in women but faster rapid<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objective</title> <p>To investigate whether otolith function (saccular and utricular) is associated with walking performance.</p> </sec> <sec> <title>Study Design</title> <p>Cross-sectional analysis of observational data collected in the Baltimore Longitudinal Study of Aging.</p> </sec> <sec> <title>Setting</title> <p>National Institute on Aging Intramural Research Program Clinical Research Unit at Harbor Hospital, Baltimore, Maryland.</p> </sec> <sec> <title>Patients</title> <p>Community-dwelling participants.</p> </sec> <sec> <title>Intervention(s)</title> <p>Cervical and ocular vestibular evoked myogenic potentials (VEMPs) were used to assess saccular and utricular function, respectively.</p> </sec> <sec> <title>Main outcome measure(s)</title> <p>Cervical and ocular VEMP latency and amplitude responses and usual, rapid, and narrow (20 cm) gait speed assessed over a 6-m course.</p> </sec> <sec> <title>Results</title> <p>In 314 participants (mean age, 73.1 yr; range, 26–96 yr), cervical VEMP amplitude mediated the association between age and gait speed—particularly narrow walk speed—in both men and women. Cervical VEMP latency had an independent association with gait speed in age-, height-, and weight-adjusted analyses, although the direction of the association differed by sex. Greater cervical VEMP latency was associated with slower usual, rapid, and narrow gait speed in women but faster rapid gait speed in men. Neither the amplitude nor latency of ocular VEMP was associated with gait speed in men or women.</p> </sec> <sec> <title>Conclusion</title> <p>These findings suggest that age-related slowing of gait speed is in part mediated by the decreased magnitude of saccular response associated with age. The sex-related differential association between saccular response latency and gait speed requires further study.</p> </sec> </abstract> … (more)
- Is Part Of:
- Otology & neurotology. Volume 36:Issue 2(2015)
- Journal:
- Otology & neurotology
- Issue:
- Volume 36:Issue 2(2015)
- Issue Display:
- Volume 36, Issue 2 (2015)
- Year:
- 2015
- Volume:
- 36
- Issue:
- 2
- Issue Sort Value:
- 2015-0036-0002-0000
- Page Start:
- Page End:
- Publication Date:
- 2015-02
- Subjects:
- Otology -- Periodicals
Ear -- Diseases -- Periodicals
Skull base -- Surgery -- Periodicals
617.8005 - Journal URLs:
- http://www.otology-neurotology.com ↗
http://journals.lww.com ↗ - DOI:
- 10.1097/MAO.0000000000000544 ↗
- Languages:
- English
- ISSNs:
- 1531-7129
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6313.528000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 2991.xml