Abdominal Circumference or Gastric Residual Volume as Measure of Feed Intolerance in VLBW Infants. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Kaur, Avneet; Kler, Neelam; Saluja, Satish; Modi, Manoj; Soni, Arun; Thakur, Anup; Garg, Pankaj
• Is Part Of: Journal of pediatric gastroenterology and nutrition. Volume 60:Issue 2(2015)
• Publication Date: 2015-02
• Subjects: Children -- Nutrition -- Periodicals; Pediatric gastroenterology -- Periodicals; Infants -- Nutrition -- Periodicals; Nutrition disorders in children -- Periodicals; Child Nutrition -- Periodicals; Digestive System -- growth & development -- Periodicals; Gastrointestinal Diseases -- Periodicals; Infant Nutrition -- Periodicals; Nutrition Disorders -- Periodicals; Child; 618.923
• DOI: 10.1097/MPG.0000000000000576
• Languages: English
• ISSNs: 0277-2116

Abstract

<abstract> <title>ABSTRACT</title> <sec> <title>Background:</title> <p>The aim of the study was to compare prefeed abdominal circumference (AC) and gastric residual volume (GRV) as a measure of feed intolerance in very-low-birth-weight infants (VLBW).</p> </sec> <sec> <title>Methods:</title> <p>Eighty VLBW infants were randomized to 2 groups; feed intolerance was monitored by measuring either GRV group or prefeed AC group. The primary outcome was time to full enteral feeds (180 mL · kg⁻¹ · day⁻¹). Other main outcome measures were feed interruption days, duration of parenteral nutrition, incidence of culture positive sepsis, necrotizing enterocolitis, mortality, and duration of hospital stay.</p> </sec> <sec> <title>Results:</title> <p>The median (interquartile range) time to achieve full feeds was 10 (9–13) versus 14 (12–17.5) days in AC and GRV groups, respectively (<italic>P</italic> &lt; 0.001). Infants in AC group had fewer feed interruption days (0 [0–2] vs 2.0 [1, 5], <italic>P</italic> &lt; 0.001) and shorter duration of parenteral nutrition (<italic>P</italic> &lt; 0.001). The incidence of culture-positive sepsis in AC and GRV groups was 17.5% and 30 %, respectively (<italic>P</italic> = 0.18). Duration of hospital stay and mortality were comparable in both the groups.</p> </sec> <sec> <title>Conclusions:</title> <p>Prefeed AC as a measure of feed intolerance in VLBW infants may shorten the time taken to achieve full feeds.</p> </sec> </abstract>