Lung Cancer Associated With Cystic Airspaces. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Mascalchi, Mario; Attinà, Domenico; Bertelli, Elena; Falchini, Massimo; Vella, Alessandra; Pegna, Andrea Lopes; Ambrosini, Valentina; Zompatori, Maurizio
• Is Part Of: Journal of computer assisted tomography. Volume 39:Issue 1(2015)
• Publication Date: 2015-01
• Subjects: Tomography -- Periodicals; Tomography -- Periodicals; Tomography; Periodicals; 616.0757
• DOI: 10.1097/RCT.0000000000000154
• Languages: English
• ISSNs: 0363-8715

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objective</title> <p>This study aimed to define computed tomographic morphologic features of lung cancer associated with cystic airspaces, their modifications in serial computed tomographic scans, and <sup>18</sup>F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography uptake.</p> </sec> <sec> <title>Methods</title> <p>Computed tomographic scans and <sup>18</sup>F-FDG positron emission tomography in 24 patients with lung cancer (17 adenocarcinomas, 7 squamous cell carcinomas, 12 stage I and 12 stage II to IV) associated with cystic airspaces were reviewed.</p> </sec> <sec> <title>Results</title> <p>Mean diameter of airspace was initially 17.6 mm (range, 5–30 mm), and 4 morphologic patterns were recognized: solid nodule protruding externally (type I, n = 5) or internally (type II, n = 4) from the cyst wall; circumferential thickening of the cyst wall (type III, n = 8); and tissue intermixed within clusters of cysts (type IV, n = 7). With tumor growth, airspace size decreased in 9, increased in 6, and was unchanged in 9 cases. Five cases evolved from type III to type I, and 5 lesions became completely solid. <sup>18</sup>F-fluoro-2-deoxy-D-glucose uptake was initially absent to mild in 7 and moderate to marked in 14 lesions.</p> </sec> <sec> <title>Conclusions</title> <p>Progressive wall thickening or appearance/increase of a nodule inside or outside a cystic airspace should raise suspicion of lung cancer irrespective of FDG uptake.</p> </sec> </abstract>