Benefit of Negative Pressure Drain Within Surgical Wound After Cytoreductive Surgery for Ovarian Cancer. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Kim, Se Ik; Lim, Myong Cheol; Bae, Hyo Sook; Shin, Se Ra; Seo, Sang-Soo; Kang, Sokbom; Park, Sang-Yoon
• Is Part Of: International journal of gynecological cancer. Volume 25:Issue 1(2015:Jan.)
• Publication Date: 2015-01
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1097/IGC.0000000000000315
• Languages: English
• ISSNs: 1048-891X

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objective</title> <p>The objective of this study was to investigate the efficacy of subcutaneous negative-pressure wound drains on wound healing after cytoreductive surgery for ovarian cancer.</p> </sec> <sec> <title>Methods</title> <p>A retrospective study was performed on patients who underwent cytoreductive surgery for epithelial ovarian cancer, between 2012 and 2013. The patients were divided into 2 groups, according to using (n = 163) and not using (n = 37) of subcutaneous wound drains, and wound outcomes were analyzed.</p> </sec> <sec> <title>Results</title> <p>Patients' characteristics were not statistically different, except for the prolonged operative time in patients with wound drains (median, 395 vs 240 minutes; <italic>P</italic> = 0.001). A lower rate of wound infection (12.9% vs 27.0%; <italic>P</italic> = 0.032) was observed in the drain group. In the multivariate analysis, placement of subcutaneous wound drain was an independent prognostic factor for reducing wound complications: disruption (odds ratio [OR], 0.367; 95% confidence interval [CI], 0.145–0.929; <italic>P</italic> = 0.034) and wound infection (OR, 0.198; 95% CI, 0.068–0.582; <italic>P</italic> = 0.003). Bowel surgery at the time of cytoreductive surgery and prolonged operative time (≥360 minutes) were also associated with higher rates of disruption (OR, 2.845; 95% CI, 1.111–7.289; <italic>P</italic> = 0.029) and wound infection (OR, 4.212; 95% CI, 1.273–13.935; <italic>P</italic> = 0.019), respectively.</p> </sec> <sec> <title>Conclusions</title> <p>Installation of subcutaneous negative-pressure wound drain is an effective method to achieve clearer wound healing and less wound complications after cytoreductive surgery for ovarian cancer.</p> </sec> </abstract>