Developmental mechanisms channeling cortical evolution. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Finlay, Barbara L.; Uchiyama, Ryutaro
• Is Part Of: Trends in neurosciences. Volume 38:Issue 2(2015)
• Page Start: 69
• Page End: 76
• Publication Date: 2015-02
• Subjects: Neurology -- Periodicals; Neurophysiology -- Periodicals; Neurobiology -- Periodicals; 612.8
• DOI: 10.1016/j.tins.2014.11.004
• Languages: English
• ISSNs: 0166-2236

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Across species, disparity in neuron number per column grows with cortical size.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">A rostrocaudal gradient in neurogenesis duration generates this disparity in neuron number.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Anisotropies in early axon extension further organize cortical area hierarchy.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">We suggest that the cortex has two zones of contrasting intrinsic topology.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">These mechanisms may progressively amplify hierarchical processing in larger brains.</p> </list-item> </list> </p> </sec> </abstract>