Corneal Thickness Differences between Sexes after Oxybuprocaine Eye Drops. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Fernandez-Garcia, Pablo; Cerviño, Alejandro; Quiles-Guiñau, Laura; Albarran-Diego, Cesar; Garcia-Lazaro, Santiago; Sanchis-Gimeno, Juan A.
• Is Part Of: Optometry and vision science. Volume 92:Issue 1(2015)
• Publication Date: 2015-01
• Subjects: Optometry -- Periodicals; Physiological optics -- Periodicals; Vision disorders -- Periodicals; 617.7505
• DOI: 10.1097/OPX.0000000000000449
• Languages: English
• ISSNs: 1040-5488

Abstract

<abstract> <title>ABSTRACT</title> <sec> <title>Purpose</title> <p>We aimed to analyze the corneal thickness (CT) values of female and male subjects before and after instillation of oxybuprocaine 0.4% anesthetic eye drops.</p> </sec> <sec> <title>Methods</title> <p>The CT of 30 female subjects and 28 male subjects was measured using scanning-slit corneal topography (Orbscan Topography System II, Orbscan, Inc, Salt Lake City, UT). Measurements were carried out before and 3 minutes after the instillation of oxybuprocaine 0.4% eye drops.</p> </sec> <sec> <title>Results</title> <p>The difference between the baseline values and those obtained after anesthesia ranged as follows: male subjects: central, −26 to +24 μm; superior, −24 to +23 μm; inferior, −19 to +20 μm; nasal, −25 to +30 μm; and temporal, −21 to +20 μm; female subjects: central, −16 to +24 μm; superior, −19 to +32 μm; inferior, −14 to +34 μm; nasal, −19 to +33 μm; and temporal, −36 to +16 μm. No significant differences were found in any corneal location in male subjects. The differences were significant at inferior (p = 0.001) and nasal (p = 0.011) corneal sites in female subjects.</p> </sec> <sec> <title>Conclusions</title> <p>Oxybuprocaine anesthetic eye drops induce significant CT increases in female subjects but not in male subjects.</p> </sec> </abstract>