The Effect of Exercise on Lipid Profiles and Inflammatory Markers in Lean Male Adolescents. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Huang, Chun-Jui; Kwok, Chin-Fai; Chou, Chung-Hsing; Chou, Yu-Ching; Ho, Low-Tone; Shih, Kuang-Chung
• Is Part Of: Journal of investigative medicine. Volume 63:Issue 1(2015:Jan.)
• Publication Date: 2015-01
• Subjects: Clinical medicine -- Periodicals; Medicine -- Research -- Periodicals; Medicine; Research -- United States; Clinical medicine; Medicine -- Research; Periodicals; 616.075
• DOI: 10.1097/JIM.0000000000000120
• Languages: English
• ISSNs: 1081-5589

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Background</title> <p>Physical activity improves body composition and inflammatory markers in obese individuals, but little is known about the nonobese population.</p> </sec> <sec> <title>Objective</title> <p>The aim of this study was to investigate associations between exercise and inflammatory cytokines in lean male adolescents in Taiwan.</p> </sec> <sec> <title>Methods</title> <p>This interventional study enrolled a total of 79 normal body weight male adolescents [mean age, 16.8 (1.0) years] from the Army Academy of Taiwan. Body composition and inflammatory markers were measured at baseline and upon completion of a 12-week exercise intervention program.</p> </sec> <sec> <title>Results</title> <p>Subjects' postintervention anthropometric measures, including waist circumference [74.6 (5.2) → 72.6 (5.2) cm], hip circumference [92.3 (4.1) → 89.9 (5.0) cm], body fat mass [10.2 (3.2) → 8.2 (3.2) kg], and body fat percentage [15.8% (4.2) → 12.6 (4.5)%] declined significantly compared to preintervention (all <italic>P</italic> < 0.001), as did systolic blood pressure (<italic>P</italic> = 0.002) and mean blood pressure (<italic>P</italic> = 0.020). Postintervention body height and free fat mass increased significantly (both <italic>P</italic> < 0.001). Subjects' postintervention lipids including total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides increased significantly (all <italic>P</italic> < 0.001). Inflammatory markers including adiponectin [14.32 (6.68) → 31.31 (30.53) μg/mL, <italic>P</italic> < 0.001], interleukin 6 [2.15 (4.81) → 2.86 (6.37) pg/mL, <italic>P</italic> = 0.005], and C-reactive protein [1.00 (2.57) → 2.30 (4.17) μg/mL, <italic>P</italic> < 0.001] increased significantly postintervention, but not leptin.</p> </sec> <sec> <title>Conclusions</title> <p>Exercise training significantly improves body composition and anti-inflammatory adiponectin levels in lean male adolescents.</p> </sec> </abstract>