Therapeutic targets for olive pollen allergy defined by gene markers modulated by Ole e 1-derived peptides. Issue 2 (April 2015)

• Record Type: Journal Article
• Authors: Calzada, David; Aguerri, Miriam; Baos, Selene; Montaner, David; Mata, Manuel; Dopazo, Joaquín; Quiralte, Joaquín; Florido, Fernando; Lahoz, Carlos; Cárdaba, Blanca
• Is Part Of: Molecular immunology. Volume 64:Issue 2(2015:Apr.)
• Page Start: 252
• Page End: 261
• Publication Date: 2015-04
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2014.12.002
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0085"> <list id="lis0010"> <list-item id="lsti0005"> <label></label> <p id="par0005">Two peptides from major allergen of olive pollen modulate the levels of Treg cytokines in allergic patients.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">These peptides change the gene-expression levels of regulation-related genes.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">These peptides could regulate the immune response in these patients.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">These results open a new research way for the regulation of this disease.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">This could be useful as new therapeutic tool for <italic>Oleacea</italic> family allergy.</p> </list-item> </list> </p> </sec> </abstract>