The activity of silver nanoparticles (Axonnite) on clinical and environmental strains of Acinetobacter spp. Issue 2 (March 2015)

• Record Type: Journal Article
• Authors: Łysakowska, Monika E.; Ciebiada-Adamiec, Anna; Klimek, Leszek; Sienkiewicz, Monika
• Is Part Of: Burns. Volume 41:Issue 2(2015)
• Page Start: 364
• Page End: 371
• Publication Date: 2015-03
• Subjects: Burns and scalds -- Periodicals; 617.11
• DOI: 10.1016/j.burns.2014.07.014
• Languages: English
• ISSNs: 0305-4179

Abstract

<abstract abstract-type="author" id="abs0005"> <title id="sect0005">Abstract</title> <sec> <p id="spar0005"> <italic>Acinetobacter baumannii</italic> isolates are responsible for a high number of wound infections. The reason of this study was to evaluate the activity of silver nanoparticles obtained by microexplosion against wide range of <italic>Acinetobacter</italic> spp. Susceptibility to silver nanoparticles was tested by microdilution method, susceptibility to antibiotics was evaluated by the disc-diffusion method. All strains of <italic>Acinetobacter</italic> spp. were sensitive to AgNPs at low concentrations. The values of the MIC for strains of <italic>Acinetobacter</italic> spp. were 0.39 and 0.78 μg/mL. In general, strains inhibited by 0.78 μg/mL of AgNPs were more resistant to antibiotics than <italic>Acinetobacter</italic> strains for which MIC = 0.39 μg/mL (<italic>p</italic> = 0.023). The AgNPs in Axonnite seems to be a good alternative for other antimicrobials to treat wound infections caused by multidrug resistant <italic>Acinetobacter</italic> spp. strains because of its high activity.</p> </sec> </abstract>