6, 6-Fused heterocyclic ureas as highly potent TRPV1 antagonists. Issue 4 (15th February 2015)

• Record Type: Journal Article
• Authors: Sun, Wei; Kim, Hyo-Shin; Lee, Sunho; Jung, Aeran; Kim, Sung-Eun; Ann, Jihyae; Yoon, Suyoung; Choi, Sun; Lee, Jin Hee; Blumberg, Peter M.; Frank-Foltyn, Robert; Bahrenberg, Gregor; Schiene, Klaus; Stockhausen, Hannelore; Christoph, Thomas; Frormann, Sven; Lee, Jeewoo
• Is Part Of: Bioorganic & medicinal chemistry letters. Volume 25:Issue 4(2015)
• Page Start: 803
• Page End: 806
• Publication Date: 2015-02-15
• Subjects: Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1016/j.bmcl.2014.12.086
• Languages: English
• ISSNs: 0960-894X

Abstract

<abstract xml:lang="en" abstract-type="graphical" id="ab005"> <title id="st005">Graphical abstract</title> <sec> <p id="sp0005">Compound <bold>15</bold><italic>K</italic>_i(ant) = 0.2 nM. <fig id="f0060" position="anchor"><graphic position="anchor" xlink:href="ark:/27927/pgh3p1gcmdv" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></fig></p> </sec> </abstract>