Bacterial and viral induction of chicken thrombocyte inflammatory responses. Issue 2 (April 2015)

• Record Type: Journal Article
• Authors: Ferdous, F.; Scott, T.
• Is Part Of: Developmental and comparative immunology. Volume 49:Issue 2(2015)
• Page Start: 225
• Page End: 230
• Publication Date: 2015-04
• Subjects: Immunology -- Periodicals; Developmental immunology -- Periodicals; 616.079
• DOI: 10.1016/j.dci.2014.11.019
• Languages: English
• ISSNs: 0145-305X

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Chicken thrombocytes express Toll-like receptors (TLRs) that are important for anti-microbial host defense.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Thrombocytes demonstrate differential responses when stimulated with various TLR ligands.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">TLR4 and TLR2 ligand stimulation increased IL-6 expression while TLR3 and TLR7/8 ligand increased nitric oxide production.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">Compared to MQ.NCSU macrophages, thrombocytes were able to respond much more rapidly when exposed to TLR ligands.</p> </list-item> </list> </p> </sec> </abstract>