Does mitigating pain decrease the risk of infection? The interactions between nociception and immune function. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Hatfield, Linda A.; Umberger, Reba
• Is Part Of: Journal of neonatal nursing. Volume 21:Issue 1(2015)
• Page Start: 11
• Page End: 17
• Publication Date: 2015-02
• Subjects: Newborn infants -- Care -- Periodicals; Newborn infants -- Diseases -- Periodicals; Neonatal intensive care -- Periodicals; Soins infirmiers en néonatologie -- Périodiques; Infant, Newborn, Diseases -- Periodicals; Intensive Care, Neonatal -- Periodicals; Neonatal Nursing -- Periodicals; 618.9200231
• DOI: 10.1016/j.jnn.2014.10.002
• Languages: English
• ISSNs: 1355-1841

Abstract

<abstract xml:lang="en" abstract-type="author" id="abs0010"> <title id="sectitle0010">Abstract</title> <sec> <p id="abspara0010">Recent studies suggest that analgesic interventions may influence immune function and the development of infection in neonates. Although substantial literature exists for the bidirectional relationship between nociception and immune pathways, there is a paucity of rigorous research linking nociception and immune function with the incidence of infection. This article presents the best available evidence for the interactions between nociception, immune function and the development of infection. Rigorous research is urgently needed to determine if anesthetic and analgesic regimens can influence immunomodulation or boost immune function significantly to avert infection.</p> </sec> </abstract>