The ratio of absolute lymphocyte count at interim of therapy to absolute lymphocyte count at diagnosis predicts survival in childhood B-lineage acute lymphoblastic leukemia. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Cheng, Yuping; Luo, Zebin; Yang, Shilong; Jia, Ming; Zhao, Haizhao; Xu, Weiqun; Tang, Yongmin
• Is Part Of: Leukemia research. Volume 39:Issue 2(2015:Feb.)
• Page Start: 144
• Page End: 150
• Publication Date: 2015-02
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2014.11.013
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We analyzed the impact of ALC-22/ALC-0 ratio on survival in 119 pediatric B-ALL patients.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">ALC-22/ALC-0 ratio &lt;10% was associated with inferior 5-year OS and EFS.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">ALC-22/ALC-0 ratio reflected the host immunity and bone marrow recovery.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">ALC was mainly associated with CD3+ T cells.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">ALC-22/ALC-0 ratio is a novel, simple and effective biomarker to predict survival.</p> </list-item> </list> </p> </sec> </abstract>