PDGFB hypomethylation is a favourable prognostic biomarker in primary myelofibrosis. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Augello, Claudia; Gianelli, Umberto; Falcone, Rossella; Tabano, Silvia; Savi, Federica; Bonaparte, Eleonora; Ciboddo, Michele; Paganini, Leda; Parafioriti, Antonina; Ricca, Dario; Lonati, Silvia; Cattaneo, Daniele; Fracchiolla, Nicola Stefano; Iurlo, Alessandra; Cortelezzi, Agostino; Bosari, Silvano; Miozzo, Monica; Sirchia, Silvia Maria
• Is Part Of: Leukemia research. Volume 39:Issue 2(2015:Feb.)
• Page Start: 236
• Page End: 241
• Publication Date: 2015-02
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2014.11.012
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We explored the DNA methylation pattern of genes encoding for cytokines and LINE-1 in primary myelofibrosis.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">PDGFB hypomethylation is a favourable prognostic factor in PMF.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">PDGF methylation status does not correlate with the presence of IDH, JAK2 or CALR genes mutations.</p> </list-item> </list> </p> </sec> </abstract>