Replication of live attenuated cold-adapted H2N2 influenza virus vaccine candidates in non human primates. Issue 1 (1st January 2015)

• Record Type: Journal Article
• Authors: Broadbent, Andrew J.; Santos, Celia P.; Paskel, Myeisha; Matsuoka, Yumiko; Lu, Janine; Chen, Zhongying; Jin, Hong; Subbarao, Kanta
• Is Part Of: Vaccine. Volume 33:Issue 1(2015)
• Page Start: 193
• Page End: 200
• Publication Date: 2015-01-01
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2014.10.065
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Non-human primates are more useful than mice or ferrets for evaluating LAIV virus replication.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Cynomolgus and rhesus macaques are preferable for evaluating H2N2 LAIV candidate virus replication.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Influenza A/Tecumseh/3/67 (H2N2) <italic>ca</italic> is a promising LAIV candidate for further evaluation.</p> </list-item> </list> </p> </sec> </abstract>