Treatment perspectives for medication-related osteonecrosis of the jaw (MRONJ). Issue 2 (March 2015)

• Record Type: Journal Article
• Authors: Ristow, Oliver; Otto, Sven; Troeltzsch, Matthias; Hohlweg-Majert, Bettina; Pautke, Christoph
• Is Part Of: Journal of cranio-maxillofacial surgery. Volume 43:Issue 2(2015:Mar.)
• Page Start: 290
• Page End: 293
• Publication Date: 2015-03
• Subjects: Skull -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Surgery, Plastic -- Periodicals; Maxilla -- surgery -- Periodicals; Face -- surgery -- Periodicals; Skull -- surgery -- Periodicals; Oral Surgical Procedures -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Surgery, Plastic -- Periodicals; Surgery, Oral -- Periodicals; Electronic journals; 617.514
• DOI: 10.1016/j.jcms.2014.11.014
• Languages: English
• ISSNs: 1010-5182

Abstract

<abstract xml:lang="en" abstract-type="author" id="abs0010"> <title id="sectitle0010">Abstract</title> <sec> <p id="abspara0010">The medication-related osteonecrosis of the jaw (MRONJ) is believed to be a therapy-resistant entity. Although the application of the recommended conservative and surgical treatment regimens have returned variable success rates, the increased awareness and experience with MRONJ suggests that surgical therapy can halt the progression of the disease, thereby allowing a histology-based diagnosis of the osteonecrosis. Surgical treatment protocols can achieve success rates of over 90% and novel techniques such as the visualization of bone fluorescence can assist in the intra-operative delineation of the osteonecrosis and standardize the procedure.</p> </sec> </abstract>