Tumor matrix protein collagen XIα1 in cancer. Issue 2 (28th February 2015)

• Record Type: Journal Article
• Authors: Raglow, Zoe; Thomas, Sufi M.
• Is Part Of: Cancer letters. Volume 357:Issue 2(2015)
• Page Start: 448
• Page End: 453
• Publication Date: 2015-02-28
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2014.12.011
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Collagen XI is a minor collagen with pathogenic roles in musculoskeletal diseases.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">ColXIα1 is overexpressed at mRNA and protein levels in many cancer types.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">ColXIα1 is highly expressed in tumor stroma, especially by tumor-associated fibroblasts.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">ColXIα1 has functional roles in cancer development and may be a therapeutic target.</p> </list-item> </list> </p> </sec> </abstract>