Increased concentration of interferon lambda-3, interferon beta and interleukin-10 in the cerebrospinal fluid of patients with tick-borne encephalitis. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Grygorczuk, Sambor; Parczewski, Miłosz; Moniuszko, Anna; Świerzbińska, Renata; Kondrusik, Maciej; Zajkowska, Joanna; Czupryna, Piotr; Dunaj, Justyna; Boroń-Kaczmarska, Anna; Pancewicz, Sławomir
• Is Part Of: Cytokine. Volume 71:Issue 2(2015)
• Page Start: 125
• Page End: 131
• Publication Date: 2015-02
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2014.10.001
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st025">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0100">IL-10, IFNλ3 and IFNβ are up-regulated in tick-borne encephalitis (TBE).</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0105">IFNλ3 and probably IFNβ and IL10 are expressed within the central nervous system.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0110">High concentration of IFNλ3 correlates with a mild clinical presentation of TBE.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0115">Genetic polymorphisms associated with IFNλ3 expression may determine the severity of TBE.</p> </list-item> </list> </p> </sec> </abstract>