An in vivo microdialysis characterization of the transient changes in the interstitial dialysate concentration of metabolites and cytokines in human skeletal muscle in response to insertion of a microdialysis probe. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Carson, Brian P.; McCormack, William G.; Conway, Clare; Cooke, John; Saunders, Jean; O'Connor, William T.; Jakeman, Philip M.
• Is Part Of: Cytokine. Volume 71:Issue 2(2015)
• Page Start: 327
• Page End: 333
• Publication Date: 2015-02
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2014.10.022
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st090">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0130">MD catheterisation of skeletal muscle causes a perturbation to tissue homeostasis.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0135">Carnosine, glutamine and taurine dialysate concentrations are elevated for up to 2 h.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0140">A sustained elevation of IL-6 and IL-8 dialysate concentrations persist for 7 h.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0145">This response occurs during apparent stable glucose and lactate metabolism.</p> </list-item> </list> </p> </sec> </abstract>