Innate stimulatory capacity of high molecular weight transition metals Au (gold) and Hg (mercury). Issue 2 (March 2015)

• Record Type: Journal Article
• Authors: Rachmawati, Dessy; Alsalem, Inás W.A.; Bontkes, Hetty J.; Verstege, Marleen I.; Gibbs, Sue; von Blomberg, B.M.E.; Scheper, Rik J.; van Hoogstraten, Ingrid M.W.
• Is Part Of: Toxicology in vitro. Volume 29:Issue 2(2015)
• Page Start: 363
• Page End: 369
• Publication Date: 2015-03
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2014.10.010
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st120">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0155">High molecular weight transitional metals Au and Hg activate innate immunity.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0160">Gold and mercury induce IL-8 secretion in myelo-monocytic cells.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0165">Stimulatory capacity of Au could be ascribed to TLR-3 ligation.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0170">Innate responses may contribute to development of oral and skin allergies.</p> </list-item> </list> </p> </sec> </abstract>