ISAV infection promotes apoptosis of SHK-1 cells through a ROS/p38 MAPK/Bad signaling pathway. Issue 1 (March 2015)

• Record Type: Journal Article
• Authors: Olavarría, Víctor H.; Recabarren, Pablo; Fredericksen, Fernanda; Villalba, Melina; Yáñez, Alejandro
• Is Part Of: Molecular immunology. Volume 64:Issue 1(2015:Mar.)
• Page Start: 1
• Page End: 8
• Publication Date: 2015-03
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2014.10.016
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">ISAv modifies the redox state of SHK-1 cells through P38 MAPK.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">ISAv induces a pro-apoptotic imbalance that leads to apoptosis.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Oxidative homeostasis regulates the survival of infected cells.</p> </list-item> </list> </p> </sec> </abstract>