The antileukoprotease secretory leukocyte protease inhibitor (SLPI) and its role in the prevention of HPV-infections in head and neck squamous cell carcinoma. Issue 1 (1st February 2015)

• Record Type: Journal Article
• Authors: Quabius, Elgar S.; Görögh, Tibor; Fischer, Gerrit S.; Hoffmann, Anna S.; Gebhard, Maximilian; Evert, Matthias; Beule, Achim; Maune, Steffen; Knecht, Rainald; Óvári, Attila; Durisin, Martin; Hoppe, Florian; Röcken, Christoph; Hedderich, Jürgen; Ambrosch, Petra; Hoffmann, Markus
• Is Part Of: Cancer letters. Volume 357:Issue 1(2015)
• Page Start: 339
• Page End: 345
• Publication Date: 2015-02-01
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2014.11.043
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">The data confirm the association between SLPI/annexin A2, Smoking and HPV-infection.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Worldwide first investigation of this kind.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">The HNSCC patient cohort represents the largest tested for these parameters ever.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">Smoking induced SLPI expression protects from HPV infections.</p> </list-item> <list-item id="u0030"> <label></label> <p id="p0030">Non-smokers are at risk of successful HPV infections due to low SLPI levels.</p> </list-item> </list> </p> </sec> </abstract>