Non transferrin bound iron (NTBI) in acute leukemias throughout conventional intensive chemotherapy: Kinetics of its appearance and potential predictive role in infectious complications. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Belotti, Angelo; Duca, Lorena; Borin, Lorenza; Realini, Silvia; Renso, Rossella; Parma, Matteo; Pioltelli, Pietro; Pogliani, Enrico; Cappellini, Maria Domenica
• Is Part Of: Leukemia research. Volume 39:Issue 1(2015:Jan.)
• Page Start: 88
• Page End: 91
• Publication Date: 2015-01
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2014.11.003
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Intensive chemotherapy causes the appearance of NTBI, independently from transfusions.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Formation of NTBI is a consequence of chemotherapy induced cell lysis.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Detectable NTBI persists throughout subsequent bone marrow myelosuppression.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">NTBI is associated with increased risk of sepsis caused by Gram negative Bacilli.</p> </list-item> </list> </p> </sec> </abstract>